Bifidobacterium animalis subsp. lactis BB-12 and Increased Salivary sIgA Levels

• Use of a probiotic mixture containing Bifidobacterium animalis subsp. lactis BB-12 and Enterococcus faecium L3 as prophylaxis to reduce the incidence of acute gastroenteritis and upper respiratory tract infections in children.

  • 2021-05
  • RCT
  • Minerva pediatrics 73(3)
  • • Francesco DI Pierro
    • Patrizia Lo Russo
    • Maria L Danza
    • Isabella Basile
    • Stefania Soardo
    • Giovanni Capocasale
    • Sandro B Paparone
    • Vittoria Paletta
    • Cosimo Lanza
    • Elvira Schiavone
    • Paolo Risso
    • Maria Colombo

  • PubMed: 32506882
  • DOI: 10.23736/s2724-5276.20.05925-3

  5 Insights on

  • Increased Salivary sIgA Levels

  • High evidence

  Salivary IgA levels significantly increased three-fold after 90 days of probiotic treatment.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes