Bifidobacterium animalis subsp. lactis BB-12 and No Significant Improvement in Global Gastrointestinal Well-being

• Effect of the probiotic strain Bifidobacterium animalis subsp. lactis, BB-12®, on defecation frequency in healthy subjects with low defecation frequency and abdominal discomfort: a randomised, double-blind, placebo-controlled, parallel-group trial.

  • 2015-09-18
  • RCT · n = 1,248
  • The British journal of nutrition 114(10)
  • • Dorte Eskesen
    • Lillian Jespersen
    • Birgit Michelsen
    • Peter J Whorwell
    • Stefan Müller-Lissner
    • Cathrine M Morberg

  • PubMed: 26382580
  • DOI: 10.1017/s0007114515003347

  5 Insights on

  • No Significant Improvement in Global Gastrointestinal Well-being

  • High evidence
  • Large Human Trial

  GI well-being, defined as global relief of abdominal discomfort, did not show significant differences.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No