Bifidobacterium animalis subsp. lactis BB-12 and Reduced Anxiety

• Bifidobacterium animalis subsp. lactis BB-12 Improves the State Anxiety and Sports Performance of Young Divers Under Stress Situations: A Single-Arm, Prospective Proof-of-Concept Study.

  • 2021-01-13
  • Clinical Trial
  • Frontiers in psychology 11
  • • Weizhong Dong
    • Ying Wang
    • Shuaixiong Liao
    • Wei Tang
    • Li Peng
    • Gang Song

  • PubMed: 33519585
  • DOI: 10.3389/fpsyg.2020.570298

  3 Insights on

  • Reduced Anxiety

  • Moderate evidence

  cognitive state anxiety, somatic state anxiety, and anxiety emotion were improved (cognitive: Z = -3.964, P < 0.001; somatic: Z = -3.079, P = 0.003; anxiety: Z = -2.973, P < 0.001)

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

  Dose

  1 × 10^9 colony-forming units/100 g daily

• ILSI Europe perspective review: site-specific microbiota changes during pregnancy associated with biological consequences and clinical outcomes: opportunities for probiotic interventions.

  • 2025-05-21
  • Review
  • Gut microbes 17(1)
  • • Eduard Flores Ventura
    • Jonathan A Lane
    • Sondra Turjeman
    • Nikoletta Vidra
    • Gisela Adrienne Weiss
    • Gabriele Gross
    • Ching-Yu Chang
    • Omry Koren

  • PubMed: 40397816
  • DOI: 10.1080/19490976.2025.2501186

  7 Insights on

  • Reduced Anxiety

  • Low evidence

  some studies suggest benefits of probiotics in reducing anxiety

  Effect

  Beneficial

  Effect size

  Small