Bifidobacterium animalis subsp. lactis BB-12 and Reduced Crying

• The therapeutic efficacy of Bifidobacterium animalis subsp. lactis BB-12® in infant colic: A randomised, double blind, placebo-controlled trial.

  • 2019-12-03
  • RCT
  • Alimentary pharmacology & therapeutics 51(1)
  • • Rita Nocerino
    • Francesca De Filippis
    • Gaetano Cecere
    • Antonio Marino
    • Maria Micillo
    • Carmen Di Scala
    • Carmen de Caro
    • Antonio Calignano
    • Cristina Bruno
    • Lorella Paparo
    • Anna M Iannicelli
    • Linda Cosenza
    • Ylenia Maddalena
    • Giusy Della Gatta
    • Serena Coppola
    • Laura Carucci
    • Danilo Ercolini
    • Roberto Berni Canani

  • PubMed: 31797399
  • DOI: 10.1111/apt.15561

  5 Insights on

  • Reduced Crying

  • High evidence
  • Rigorous Journal

  The mean number of crying episodes decreased in both groups, but with a higher effect in BB-12 group (-4.7 ± 3.4 vs -2.3 ± 2.2, P < 0.05).

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes