Bifidobacterium animalis subsp. lactis BB-12 and Reduced Inflammation Around Wounds

• Lactobacillus rhamnosus GG and Bifidobacterium animalis subsp. lactis BB-12 promote infected wound healing via regulation of the wound microenvironment.

  • 2024-10
  • Microbial biotechnology 17(10)
  • • Zhe Yin
    • Yilin Wang
    • Xiaojuan Feng
    • Changqing Liu
    • Xiaoyang Guan
    • Shuyan Liu
    • Zhanyi Long
    • Zhonghua Miao
    • Fang He
    • Ruyue Cheng
    • Yanting Han
    • Ka Li

  • PubMed: 39422648
  • DOI: 10.1111/1751-7915.70031

  4 Insights on

  • Reduced Inflammation Around Wounds

  • Low evidence
  • Animal Study

  LGG and BB-12 both effectively inhibited neutrophil infiltration and decreased the expression of pro-inflammatory cytokines tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6). Notably, BB-12 markedly reduced IL-6 levels

  Effect

  Beneficial

  Effect size

  Moderate