Impact of orally administered lozenges with Lactobacillus rhamnosus GG and Bifidobacterium animalis subsp. lactis BB-12 on the number of salivary mutans streptococci, amount of plaque, gingival inflammation and the oral microbiome in healthy adults.
- 2014-03-18
- RCT · n = 31
- Clinical oral investigations 19(1)
- Aino Toiviainen
- Heli Jalasvuori
- Emilia Lahti
- Ulvi Gursoy
- Seppo Salminen
- Margherita Fontana
- Susan Flannagan
- George Eckert
- Alexis Kokaras
- Bruce Paster
- Eva Söderling
- PubMed: 24638207
- DOI: 10.1007/s00784-014-1221-6
- High evidence
The probiotic lozenge decreased both PI and GI (p < 0.05) while no changes were observed in the control group.
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes