Bifidobacterium animalis subsp. lactis BB-12 and Reduced Pro-Inflammatory Immune Activity

• Consumption of Bifidobacterium animalis subsp. lactis BB-12 in yogurt reduced expression of TLR-2 on peripheral blood-derived monocytes and pro-inflammatory cytokine secretion in young adults

  • 2015-11-30
  • RCT · n = 30
  • European Journal of Nutrition 56(2)
  • • Huicui Meng
    • Zhaoyong Ba
    • Yujin Lee
    • Jiayu Peng
    • Junli Lin
    • J. Fleming
    • E. Furumoto
    • R. Roberts
    • P. Kris-Etherton
    • C. Rogers

  • PubMed: 26621631
  • DOI: 10.1007/s00394-015-1109-5

  8 Insights on

  • Reduced Pro-Inflammatory Immune Activity

  • High evidence
  • Rigorous Journal
  • Adults

  Participants who consumed yogurt smoothie with BB-12 added post-fermentation had significantly lower expression of TLR-2 on CD14+HLA-DR+ cells and reduction in TNF-α secretion from BB-12- or LPS-stimulated PBMCs compared to baseline.

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes