Synbiotic combination of 2'-fucosyllactose and Bifidobacterium mitigates neurodevelopmental disorders and ASD-like behaviors induced by valproic acid.
- 2025
- Food & function 16(7)
- Ying He
- Bo Zhang
- Yu Xin
- Wenxiu Wang
- Xue Wang
- Zhuo Liu
- Yongbo She
- Rui Guo
- Gengjie Jia
- Shan Wu
- Zhigang Liu
- PubMed: 40165714
- DOI: 10.1039/d4fo06234e
- Low evidence
- Rigorous Journal
- Animal Study
outperformed that of 2'-FL and Lactobacillus paracasei L9300BH (L9300BH) in alleviating social deficits, repetitive behaviors, neuronal damage, and dysregulated expression of social-related genes and neuroinflammatory markers in ASD mice
- Effect
- Beneficial
- Effect size
- Large