Bifidobacterium animalis subsp. lactis BB-12 and Reduced Symptom Severity

• Probiotic Blend of Lactobacillus acidophilus LA-5 and Bifidobacterium animalis ssp. Lactis BB-12 in Non-constipated Irritable Bowel Syndrome: A Double-Blind Randomized Placebo-Controlled Trial.

  • 2025-11-18
  • RCT
  • Journal of gastroenterology and hepatology 41(1)
  • • Uday C Ghoshal
    • B S Ramakrishna
    • Pravin M Rathi
    • Akash Shukla
    • Manas Kumar Panigrahi
    • Shubham Jain
    • Indraneel Saha
    • Karmabir Chakravartty
    • Madhuri Singh
    • Uzma Mustafa
    • Shikha Sahu
    • Ujjala Ghoshal
    • Sanjay Chandnani
    • Mahesh K Goenka
    • Monjori Mitra

  • PubMed: 41255078
  • DOI: 10.1111/jgh.70137

  6 Insights on

  • Reduced Symptom Severity

  • High evidence

  The percentage of patients with "severe" symptoms reduced from 20.8% at baseline to 3.9% at day 84

  Effect

  Beneficial

  Effect size

  Moderate