Bifidobacterium animalis subsp. lactis HN019 and Improved Apical Periodontitis Histological Status

• Effect of systemic administration of Bifidobacterium animalis subsp. lactis HN019 on apical periodontitis.

  • 2023-11-27
  • Brazilian oral research 37
  • • Lisa Danielly Curcino Araujo
    • Raquel Assed Bezerra Segato
    • Thaís de Paula Colen Reis
    • Sérgio Luis de Souza Salvador
    • Flávia Aparecida Chaves Furlaneto
    • Michel Reis Messora
    • Paulo Nelson-Filho
    • Lana Kei Yamamoto de Almeida
    • Marília Pacífico Lucisano
    • Clara Marina Pereira Cavalcanti Silva
    • Léa Assed Bezerra da Silva

  • PubMed: 37970935
  • DOI: 10.1590/1807-3107bor-2023.vol37.0115

  1 Insight on

  • Improved Apical Periodontitis Histological Status

  • Low evidence
  • Animal Study

  Although no statistical differences were observed, the groups administered with probiotics showed better conditions in terms of histological aspects seen microscopically. Furthermore, there were no differences in the number of osteoclasts (p > 0.05). The RANKL marker was not found in the probiotic group at 42 days, unlike in group III.

  Effect

  Beneficial

  Effect size

  Small

  Significant

  No