Bifidobacterium animalis subsp. lactis HN019 and Improved Bowel Function Index

• Effects of 28-day Bifidobacterium animalis subsp. lactis HN019 supplementation on colonic transit time and gastrointestinal symptoms in adults with functional constipation: A double-blind, randomized, placebo-controlled, and dose-ranging trial

  • 2018-02-08
  • RCT · n = 228
  • Gut Microbes 9(3)
  • • A. Ibarra
    • Mathilde Latreille-Barbier
    • Y. Donazzolo
    • X. Pelletier
    • A. Ouwehand

  • PubMed: 29227175
  • DOI: 10.1080/19490976.2017.1412908

  22 Insights on

  • Improved Bowel Function Index

  • High evidence
  • Rigorous Journal
  • Clinical

  There were no statistically significant differences in the primary or secondary outcomes between interventions.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

  Dose

  1 × 10^9 or 1 × 10^10 CFU/day