Bifidobacterium animalis subsp. lactis and Improved Constipation Symptoms

• The adjunct use of Bifidobacterium animalis subsp. lactis BAMA-B06/BAu-B0111 improves the therapeutic efficacy of Liuwei'anxiao Capsule in alleviating constipation in Parkinson's Disease: A randomized controlled study.

  • 2026-08
  • RCT · n = 105
  • Journal of ethnopharmacology 367
  • • Ming Lin
    • Shengjie Li
    • Jieyu Lin
    • Jiayi Wan
    • Tangchang Xu
    • Xinyue Qi
    • Jing Wei
    • Jian Li
    • Tingtao Chen
    • Huaijun Tu

  • PubMed: 41990927
  • DOI: 10.1016/j.jep.2026.121694

  3 Insights on

  • Improved Constipation Symptoms

  • High evidence

  The adjunct use of a probiotic strain Bifidobacterium animalis subsp. lactis BAMA-B06/BAu-B0111 was employed to potentiate the efficacy of LAC in relieving Parkinson's disease (PD) constipation... All groups showed significant improvements in Wexner and PAC-QOL scores and increased weekly SBM frequency (P < 0.001)... The overall effective rates of constipation improvement were 60.00%, 56.67%, and 72.41% for the L, P, and LP groups, respectively.

  Effect

  Beneficial

  Effect size

  Moderate