Bifidobacterium animalis subsp. lactis and Improved Immune Organ Development

• Bifidobacterium animalis subsp. lactis modulates early-life immune response and gut metabolism.

  • 2025-05-28
  • Animal models and experimental medicine 8(6)
  • • Haoming Du
    • Yiran Cai
    • Lulu Shen
    • Yuxing Zheng
    • Lingling Zhao
    • Ruibiao Hu
    • Shan Jiang
    • Jiajia Yuan
    • Chengming Hu
    • Qi Deng
    • Jiaoyan Huang
    • Jingbo Hu
    • Yuexiang Wang
    • Jing Tan
    • Jiahui Chen
    • Feitong Liu
    • Yuanyuan Duan
    • Haitao Niu

  • PubMed: 40437776
  • DOI: 10.1002/ame2.70034

  2 Insights on

  • Improved Immune Organ Development

  • Low evidence
  • Animal Study

  BB-12 effectively modulates the gut immune microenvironment, leading to beneficial changes in T-cell subsets in key immune tissues such as the spleen, thymus, and gut IELs.

  Effect

  Beneficial

  Effect size

  Moderate