Bifidobacterium animalis subsp. lactis and Modulated Maternal Immune Response

• Bifidobacterium animalis subsp. Lactis BL-99 Improves Maternal and Fetal Immune Responses and Pregnancy Outcomes in Pregnant Antibiotics-Treated Mice.

  • 2025-09-04
  • Molecular nutrition & food research 69(21)
  • • Marijke M Faas
    • Lieske Wekema
    • Carolien A van Loo-Bouwman
    • Gisela A Weiss
    • Wei-Lian Hung
    • Bart J de Haan
    • Alexandra M Smink

  • PubMed: 40906440
  • DOI: 10.1002/mnfr.70220

  3 Insights on

  • Modulated Maternal Immune Response

  • Low evidence
  • Rigorous Journal
  • Animal Study

  BL-99 ... improved maternal immune responses by decreasing splenic Th1 cells and Treg cells, and increasing FoxP3/RoRγT double-positive cells in the Peyer's patches to levels observed in control pregnant mice.

  Effect

  Beneficial

  Effect size

  Moderate