Network meta-analysis of randomized control trials evaluating the effectiveness of various probiotic formulations in patients with type 2 diabetes mellitus.
- 2025-07-11
- Review · n = 62
- Diabetology & metabolic syndrome 17(1)
- Abdallah R Allam
- Mohamed Basyouni Helal
- Mohamed Salah Alhateem
- Mohamed Ashraf Shehab
- Ahmed Gamal Elshaar
- Mohamed Ahmed Saeda
- Fatma Magdi Ibrahim
- Ahmed Maher Khalil
- Abdelrahman Mohamed Mahmoud
- PubMed: 40646644
- DOI: 10.1186/s13098-025-01841-2
- Moderate evidence
Among all interventions, the combination of Bifidobacterium bifidum W23, Bifidobacterium lactis W52, Lactobacillus acidophilus W37, Lactobacillus brevis W63, Lactobacillus casei W56, Lactobacillus salivarius W24, Lactococcus lactis W19, and Lactococcus lactis W58 achieved the greatest reduction in fasting plasma glucose (FPG) [MD = - 73.50; 95% CI: - 113.13 to - 33.86].
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes