Bifidobacterium bifidum G9-1 and Improved Estimated Glomerular Filtration Rate

• Efficacy of probiotics (Bifidobacterium bifidum G9-1) in patients with type 2 diabetes mellitus and chronic kidney disease complicated by constipation: An exploratory, multicenter, open-label, single-arm study (BIRDIE study).

  • 2026-01-08
  • Clinical Trial · n = 30
  • Journal of diabetes investigation 17(3)
  • • Fuki Ikeda
    • Junko Sato
    • Hidenori Yoshii
    • Masahiro Sugawara
    • Hiroaki Satoh
    • Yukiko Sugawara
    • Hirotsugu Uzawa
    • Daisuke Sugimoto
    • Reina Muto
    • Yuya Nishida
    • Hirotaka Watada

  • PubMed: 41504339
  • DOI: 10.1111/jdi.70236

  14 Insights on

  • Improved Estimated Glomerular Filtration Rate

  • High evidence

  Glycated hemoglobin and the estimated glomerular filtration rate did not change significantly

  Effect

  Neutral

  Effect size

  Small

  Significant

  No