Bifidobacterium bifidum MAK53B66B and Improved Spatial Learning Ability

• An 8-Week Administration of Bifidobacterium bifidum and Lactobacillus plantarum Combined with Exercise Training Alleviates Neurotoxicity of Aβ and Spatial Learning via Acetylcholine in Alzheimer Rat Model

  • 2021-03-14
  • RCT · n = 25
  • Journal of Molecular Neuroscience 71(7)
  • • Samaneh Shamsipour
    • G. Sharifi
    • F. Taghian

  • PubMed: 33715084
  • DOI: 10.1007/s12031-021-01812-y

  5 Insights on

  • Improved Spatial Learning Ability

  • Low evidence
  • Rigorous Journal
  • Animal Study
  • Clinical

  The combined use of probiotics and exercise training significantly increased the time spent in the target quadrant after removing the platform, compared with the AD group in the Morris water maze test (p < 0.001).

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes