Anti-Tumor Effect of Heat-Killed Bifidobacterium bifidum on Human Gastric Cancer through Akt-p53-Dependent Mitochondrial Apoptosis in Xenograft Models
- 2022-08-29
- Clinical Trial
- International Journal of Molecular Sciences 23(17)
- SukJin Kim
- H. H. Lee
- Wonhyeok Choi
- Chang-Ho Kang
- Gun-Hee Kim
- Hyosun Cho
- PubMed: 36077182
- DOI: 10.3390/ijms23179788
- Low evidence
- Animal Study
Oral administration of a single dose or a mixture of MG731, MG5346, or MG5200 significantly delayed tumor growth, and MG731 had the most effective anti-tumor effect in the xenograft model.
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes