Bifidobacterium bifidum Rosell-71 and Improved Cognitive Function

• Role of Probiotics in Management of Depressive Symptoms and Cognitive Impairment in Patients With Depression: An Updated Analysis of Trials.

  • 2025-11-29
  • Meta-Analysis
  • Brain and behavior 15(12)
  • • Syed Ali Arsal
    • Aashish Kumar
    • Umer Iqbal
    • Shafin Bin Amin
    • Muhammad Aniq Amir
    • Muhammad Abrar Amir
    • Muhammad Ashir Shafique
    • Suhaib Ahmed
    • Laksh Kumar
    • Oluwatobiloba Israel Popoola
    • Inibehe Ime Okon

  • PubMed: 41319022
  • DOI: 10.1002/brb3.71108

  2 Insights on

  • Improved Cognitive Function

  • High evidence

  Patients receiving probiotics had significant alleviation of cognitive symptoms (p = 0.01; SMD, -0.90; 95% confidence interval [CI], -1.59 to -0.21; I2 = 82%) in comparison to placebo

  • Beneficial
  • Large effect
  • Significant

• Probiotic supplementation for optimizing athletic performance: current evidence and future perspectives for microbiome-based strategies.

  • 2025-07-15
  • Review
  • Frontiers in nutrition 12
  • • Timea Teglas
    • Zsolt Radak

  • PubMed: 40735239
  • DOI: 10.3389/fnut.2025.1572687

  10 Insights on

  • Improved Cognitive Function

  • Low evidence

  it appears that probiotics have a beneficial effect on mental health, cognitive functions, sleep, gastrointestinal, and upper respiratory symptoms in adult humans.

  • Beneficial
  • Small effect

• Synbiotics in Alzheimer's disease: mechanisms, clinical evidence, and therapeutic prospects.

  • 2025-09-24
  • Review
  • Journal of translational medicine 23(1)
  • • Yuhua Lin
    • Rongping Weng
    • Huayang Pan
    • Yangbo Hou
    • Yipeng Sun
    • Junkai Wen

  • PubMed: 40993787
  • DOI: 10.1186/s12967-025-07064-3

  5 Insights on

  • Improved Cognitive Function

  • Low evidence

  Synbiotics demonstrate significant potential, particularly in early AD, by improving cognitive domains, reducing neuroinflammation and AD biomarkers, and modulating beneficial microbial metabolites.

  • Beneficial
  • Moderate effect