Bifidobacterium bifidum Rosell-71 and Reduced Alzheimer’s Disease Pathology

• Synbiotics in Alzheimer's disease: mechanisms, clinical evidence, and therapeutic prospects.

  • 2025-09-24
  • Review
  • Journal of translational medicine 23(1)
  • • Yuhua Lin
    • Rongping Weng
    • Huayang Pan
    • Yangbo Hou
    • Yipeng Sun
    • Junkai Wen

  • PubMed: 40993787
  • DOI: 10.1186/s12967-025-07064-3

  5 Insights on

  • Reduced Alzheimer’s Disease Pathology

  • Low evidence

  Synbiotics demonstrate significant potential, particularly in early AD, by improving cognitive domains, reducing neuroinflammation and AD biomarkers, and modulating beneficial microbial metabolites.

  Effect

  Beneficial

  Effect size

  Moderate