Bifidobacterium bifidum VPro 51 and Improved Survival of Probiotic Bacteria

• Increase of intestinal Bifidobacterium and suppression of coliform bacteria with short-term yogurt ingestion.

  • 1999-11
  • Clinical Trial · n = 34
  • Journal of Dairy Science 82(11)
  • • R. M. Chen
    • J. Wu
    • S. C. Lee
    • A. Huang
    • H. Wu

  • PubMed: 10575598
  • DOI: 10.3168/JDS.S0022-0302(99)75479-2

  3 Insights on

  • Improved Survival of Probiotic Bacteria

  • High evidence

  Arbitrarily primed polymerase chain reaction was used to differentiate the identity of bifidobacteria in four volunteers before and after yogurt ingestion and confirmed that B. bifidum ingested from the yogurt survived and proliferated in the stool throughout the experiment.

  Effect

  Beneficial

  Effect size

  Moderate

• Protection of bifidobacteria encapsulated in polysaccharide-protein gel beads against gastric juice and bile.

  • 2003-11
  • Journal of Food Protection 66(11)
  • • D. Guérin
    • J. Vuillemard
    • M. Subirade

  • PubMed: 14627286
  • DOI: 10.4315/0362-028X-66.11.2076

  2 Insights on

  • Improved Survival of Probiotic Bacteria

  • Low evidence
  • Highly Cited

  After 1 h in an acidic solution (pH 2.5), the free-cell counts decreased by 4.75 log units, compared with a <1-log decrease for entrapped cells. The free cells did not survive after 2 h of incubation at pH 2.5, while immobilized-cell counts decreased by about 2 log units.

  Effect

  Beneficial

  Effect size

  Large