Bifidobacterium bifidum and Improved Chronic Kidney Disease Outcomes

• ILA-producing bifidobacterium bifidum ameliorates chronic kidney disease via AHR signaling by modulating the gut-kidney axis.

  • 2026-04
  • Food research international (Ottawa, Ont.) 230
  • • Qinglian Hua
    • Yang Meng
    • Jinpeng Hu
    • Yanchen Wei
    • Huaxi Yi
    • Xi Liang
    • Lanwei Zhang
    • Zhe Zhang

  • PubMed: 41794500
  • DOI: 10.1016/j.foodres.2026.118638

  4 Insights on

  • Improved Chronic Kidney Disease Outcomes

  • Low evidence
  • Animal Study

  ZL.1 exhibited pronounced efficacy: it not only improved renal injury, restored gut barrier function, and corrected dysbiosis... In conclusion, our study suggests that ILA-producing B. bifidum may ameliorate CKD by regulating the gut-kidney axis via ILA and AHR signaling.

  Effect

  Beneficial

  Effect size

  Large