Interventions Targeting the Gut Microbiome to Improve Cancer Treatment Outcomes and Their Gastrointestinal Side Effects: A Systematic Review and Meta-analysis.
- 2026-02
- Meta-Analysis · n = 37
- The Journal of nutrition 156(2)
- Cecilia Morel
- Ruijie Li
- Carmen Fiuza Luces
- Mark Fh Brougham
- Juan Francisco Pascual-Gazquez
- Luciana Torquati
- Raquel Revuelta Iniesta
- PubMed: 41475679
- DOI: 10.1016/j.tjnut.2025.101300
- High evidence
Emerging evidence highlights the role of the gut microbiome (GM) in influencing treatment responses and modulating gastrointestinal adverse events (GIAEs). Because cancer therapy disrupts GM composition, restoring gut health may help mitigate side effects and support gut-associated immunity.
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes