Bifidobacterium breve Bb-18 and No Significant Change in IgE Levels

• Impact of Probiotics on Atopic Dermatitis in Pediatric Patients: A Systematic Review and Meta-Analysis.

  • 2025-11-24
  • Meta-Analysis
  • Medicina (Kaunas, Lithuania) 61(12)
  • • Ritu Gaikwad
    • Soham Kondle
    • Sean Chang
    • Chris Barnes
    • Rohan Kubba
    • Christopher Lane
    • Snigdha Uppu
    • Eldo Frezza

  • PubMed: 41470092
  • DOI: 10.3390/medicina61122090

  5 Insights on

  • No Significant Change in IgE Levels

  • High evidence

  Secondary analysis of IgE changes showed a non-significant effect (g ≈ 0.15, p = 0.13), possibly due to short study durations (mean 12 weeks).

  Effect

  Neutral

  Effect size

  Small

  Significant

  No