Bifidobacterium breve Bb-18 and Reduced Atopic Dermatitis Severity

• The impact of prebiotics, probiotics and synbiotics on the prevention and treatment of atopic dermatitis in children: an umbrella meta-analysis.

  • 2025-03-21
  • Systematic Review · n = 150
  • Frontiers in pediatrics 13
  • • Lifeng Wang
    • Lijuan Xu

  • PubMed: 40191649
  • DOI: 10.3389/fped.2025.1498965

  3 Insights on

  • Reduced Atopic Dermatitis Severity

  • High evidence

  The treatment significantly reduced SCORAD score (WMD = -3.75, 95% CI: -5.08 to -2.42).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

• Impact of Probiotics on Atopic Dermatitis in Pediatric Patients: A Systematic Review and Meta-Analysis.

  • 2025-11-24
  • Meta-Analysis
  • Medicina (Kaunas, Lithuania) 61(12)
  • • Ritu Gaikwad
    • Soham Kondle
    • Sean Chang
    • Chris Barnes
    • Rohan Kubba
    • Christopher Lane
    • Snigdha Uppu
    • Eldo Frezza

  • PubMed: 41470092
  • DOI: 10.3390/medicina61122090

  5 Insights on

  • Reduced Atopic Dermatitis Severity

  • High evidence

  Pooled analysis using a random-effects model (Hedges' g ≈ 0.65, p < 0.05) indicated a moderate to large improvement in AD severity with probiotic therapy.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes