Bifidobacterium breve BR03 and Improved Th17/Treg Ratio

• Probiotics reduce gut microbial translocation and improve adult atopic dermatitis.

  • 2012-10
  • RCT
  • Journal of clinical gastroenterology 46
  • • Enrico Iemoli
    • Daria Trabattoni
    • Serena Parisotto
    • Linda Borgonovo
    • Marco Toscano
    • Giuliano Rizzardini
    • Mario Clerici
    • Elena Ricci
    • Alessandra Fusi
    • Elena De Vecchi
    • Stefania Piconi
    • Lorenzo Drago

  • PubMed: 22955355
  • DOI: 10.1097/mcg.0b013e31826a8468

  6 Insights on

  • Improved Th17/Treg Ratio

  • High evidence
  • Clinical

  The probiotics reduced microbial translocation (P=0.050), immune activation (P<0.001), improved T-helper cell (Th)17/regulatory T cell (Treg) (P=0.029) and Th1/Th2 (P=0.028) ratios.

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes