Bifidobacterium breve MAK40B22B and Increased Epithelial Proliferation in the Small Intestine

• Synbiotic promotion of epithelial proliferation by orally ingested encapsulated Bifidobacterium breve and raffinose in the small intestine of rats.

  • 2009-05
  • RCT
  • Molecular Nutrition & Food Research 53(S1)
  • • S. Ishizuka
    • Ami Iwama
    • A. Dinoto
    • A. Suksomcheep
    • K. Maeta
    • T. Kasai
    • H. Hara
    • A. Yokota

  • PubMed: 18837471
  • DOI: 10.1002/mnfr.200800041

  1 Insight on

  • Increased Epithelial Proliferation in the Small Intestine

  • High evidence
  • Clinical

  Epithelial proliferation in the small intestine, as assessed by bromodeoxyuridine immunohistochemistry, was increased only in the B. breve plus raffinose-fed group.

  Effect

  Beneficial

  Effect size

  Large