Bifidobacterium breve MAK40B22B and Reduced Eosinophilic Inflammation

• Maternal supplementation with Bifidobacterium breve M-16V prevents their offspring from allergic airway inflammation accelerated by the prenatal exposure to an air pollutant aerosol

  • 2020-09-11
  • Clinical Trial
  • PLOS ONE 15(9)
  • • Chiyoko Terada-Ikeda
    • M. Kitabatake
    • A. Hiraku
    • Kumiko Kato
    • Satsuki Yasui
    • N. Imakita
    • N. Ouji-Sageshima
    • N. Iwabuchi
    • K. Hamada
    • Toshihiro Ito

  • PubMed: 32915886
  • DOI: 10.1371/journal.pone.0238923

  9 Insights on

  • Reduced Eosinophilic Inflammation

  • Low evidence
  • Rigorous Journal
  • Animal Study

  The intake of B. breve M-16V in residual oil fly ash (ROFA)-exposed pregnant mice resulted in fewer eosinophils in the bronchoalveolar lavage fluid of neonatal mice and reduced allergic lung inflammation.

  Effect

  Beneficial

  Effect size

  Moderate