Bifidobacterium breve Rosell-70 and Improved Sleep Quality

• Evaluating the Impact of Probiotic Therapy on the Endocannabinoid System, Pain, Sleep and Fatigue: A Randomized, Double-Blind, Placebo-Controlled Trial in Dancers.

  • 2024-05-21
  • RCT
  • International journal of molecular sciences 25(11)
  • • Jakub Wiącek
    • Tomasz Podgórski
    • Krzysztof Kusy
    • Igor Łoniewski
    • Karolina Skonieczna-Żydecka
    • Joanna Karolkiewicz

  • PubMed: 38891799
  • DOI: 10.3390/ijms25115611

  1 Insight on

  • Improved Sleep Quality

  • High evidence
  • Rigorous Journal

  A trend toward improved sleep quality was observed in the probiotic group, while the placebo group showed a decline (PRO: from 1.4 to 1.0; PLA: from 0.8 to 1.2; p = 0.07841).

  Effect

  Beneficial

  Effect size

  Small

  Significant

  No

• Insomnia: the gut microbiome connection, prospects for probiotic and postbiotic therapies, and future directions.

  • 2026-04
  • Review
  • Journal of advanced research 82
  • • Qiong Wu
    • Guangqi Gao
    • Lai-Yu Kwok
    • Huimin Lv
    • Zhihong Sun

  • PubMed: 40651630
  • DOI: 10.1016/j.jare.2025.07.005

  2 Insights on

  • Improved Sleep Quality

  • Low evidence

  Probiotics and postbiotics are beneficial microorganisms and their components and metabolites, which offer potential in modulating the gut microbiota of the host and alleviating insomnia. ... Probiotics can regulate sleep-wake behavior by modulating gut microbiota and its metabolites, influencing endocrine, neuronal, and immune responses.

  Effect

  Beneficial

  Effect size

  Moderate