Effects of Bifidobacterium breve A1 on the cognitive function of older adults with memory complaints: a randomised, double-blind, placebo-controlled trial.
- 2019-05-28
- RCT · n = 121
- Beneficial Microbes 10(5)
- Y. Kobayashi
- T. Kuhara
- M. Oki
- J.‐Z. Xiao
- PubMed: 31090457
- DOI: 10.3920/BM2018.0170
- High evidence
- Highly Cited
- Clinical
However, a stratified analysis revealed a significant difference between *B. breve* A1 and placebo groups in terms of the subscale 'immediate memory' of RBANS and MMSE total score in the subjects with low RBANS total score at baseline.
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes