Bifidobacterium breve VPro 52 and Reduced Brain Atrophy

• Effect of Probiotic Bifidobacterium breve in Improving Cognitive Function and Preventing Brain Atrophy in Older Patients with Suspected Mild Cognitive Impairment: Results of a 24-Week Randomized, Double-Blind, Placebo-Controlled Trial

  • 2022-06-28
  • RCT · n = 130
  • Journal of Alzheimer's Disease 88(1)
  • • D. Asaoka
    • Jinzhong Xiao
    • T. Takeda
    • N. Yanagisawa
    • Takahiro Yamazaki
    • Yoichiro Matsubara
    • Hideki Sugiyama
    • Noemi Endo
    • Motoyuki Higa
    • K. Kasanuki
    • Y. Ichimiya
    • S. Koido
    • Kazuya Ohno
    • François Bernier
    • N. Katsumata
    • A. Nagahara
    • H. Arai
    • T. Ohkusa
    • Nobuhiro Sato

  • PubMed: 35570493
  • DOI: 10.3233/jad-220148

  4 Insights on

  • Reduced Brain Atrophy

  • High evidence
  • Rigorous Journal

  Probiotics consumption for 24 weeks suppressed brain atrophy progression, suggesting that B. breve MCC1274 helps prevent cognitive impairment of MCI subjects.

  Effect

  Beneficial

  Effect size

  Moderate