Bifidobacterium infantis MAK22B041 and Promoted Weight Gain

• Bifidobacterium infantis treatment promotes weight gain in Bangladeshi infants with severe acute malnutrition

  • 2022-04-13
  • RCT
  • Science Translational Medicine 14(640)
  • • Michael J. Barratt
    • Sharika Nuzhat
    • Kazi Ahsan
    • S. Frese
    • Aleksandr A. Arzamasov
    • S. Sarker
    • M. M. Islam
    • P. Palit
    • Md. Ridwan Islam
    • M. Hibberd
    • Swetha Nakshatri
    • Carrie A. Cowardin
    • J. Guruge
    • A. Byrne
    • Siddarth Venkatesh
    • Vinaik Sundaresan
    • B. Henrick
    • R. Duar
    • Ryan D. Mitchell
    • G. Casaburi
    • Johann Prambs
    • Robin L. Flannery
    • M. Mahfuz
    • D. Rodionov
    • A. Osterman
    • David Kyle
    • T. Ahmed
    • J. Gordon

  • PubMed: 35417188
  • DOI: 10.1126/scitranslmed.abk1107

  3 Insights on

  • Promoted Weight Gain

  • Low evidence
  • Rigorous Journal
  • Animal Study
  • Clinical

  EVC001 treatment promoted weight gain that was associated with reduced intestinal inflammation markers in infants with SAM.

  Effect

  Beneficial

  Effect size

  Moderate