Bifidobacterium infantis VPro 53 and Reduced Risk of Necrotizing Enterocolitis

• Bifidobacterium may benefit the prevention of necrotizing enterocolitis in preterm infants: A systematic review and meta-analysis.

  • 2019-01
  • Meta-Analysis
  • International Journal of Surgery 61
  • • Xiu-li Zhu
    • Xiao-Gang Tang
    • Fan Qu
    • Yu Zheng
    • Wenhao Zhang
    • Yu-qiao Diao

  • PubMed: 30500473
  • DOI: 10.1016/j.ijsu.2018.11.026

  7 Insights on

  • Reduced Risk of Necrotizing Enterocolitis

  • High evidence

  When comparing Bifidobacterium groups with control groups, the relative risk of developing NEC (RR 0.38, 95% CI 0.25-0.58; P < 0.00001) was significantly lower in the Bifidobacterium groups.

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

• Bifidobacterium longum subspecies infantis: champion colonizer of the infant gut

  • 2014-10-10
  • Pediatric Research 77(1-2)
  • • M. Underwood
    • J. German
    • C. Lebrilla
    • D. Mills

  • PubMed: 25303277
  • DOI: 10.1038/pr.2014.156

  16 Insights on

  • Reduced Risk of Necrotizing Enterocolitis

  • Moderate evidence
  • Highly Cited
  • Rigorous Journal

  Probiotics containing B. infantis decrease the risk of necrotizing enterocolitis in premature infants.

  Effect

  Beneficial

  Effect size

  Large