Bifidobacterium infantis VPro 53 and Reduced Risk of Necrotizing Enterocolitis Surgery

• Prophylactic use of Lactobacillus acidophilus/Bifidobacterium infantis probiotics and outcome in very low birth weight infants.

  • 2014-08
  • Observational · n = 5,351
  • The Journal of Pediatrics 165(2)
  • • C. Härtel
    • Julia Pagel
    • J. Rupp
    • M. Bendiks
    • F. Guthmann
    • E. Rieger-Fackeldey
    • M. Heckmann
    • A. Franz
    • J. Schiffmann
    • Beate Zimmermann
    • N. Hepping
    • A. von der Wense
    • C. Wieg
    • E. Herting
    • W. Göpel

  • PubMed: 24880888
  • DOI: 10.1016/j.jpeds.2014.04.029

  10 Insights on

  • Reduced Risk of Necrotizing Enterocolitis Surgery

  • High evidence
  • Highly Cited

  The use of probiotics was associated with a reduced risk for necrotizing enterocolitis surgery (group 1 vs group 3: 4.2 vs 2.6%, P=.028; change of strategy: 6.2 vs 4.0%, P<.001).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes