Bifidobacterium infantis and Increased Oxidative Stress

• Bifidobacterium Infantis Promotes FOSL1-Mediated Transcriptional Repression of VDR to Accelerate Autoimmune Pancreatitis Progression Through Activation of Oxidative Stress.

  • 2026-01-23
  • Inflammation 49(1)
  • • Jie Tang
    • Qin Li
    • Kai Li
    • Dongyun Hang
    • Danyin Gu
    • Lingmei Feng
    • Guoyu Chen
    • Ming Xu

  • PubMed: 41572095
  • DOI: 10.1007/s10753-025-02368-4

  2 Insights on

  • Increased Oxidative Stress

  • Low evidence

  B. infantis-stimulated activation of pDCs was mediated by FOSL1-inhibited VDR transcription, which promoted oxidative stress.

  Effect

  Harmful

  Effect size

  Moderate