Multistrain Probiotics Plus Vitamin D Improve Gut Barrier Function and Gut Microbiota Composition in Irritable Bowel Syndrome Without Constipation: Results from a Double-Blind, Randomized, Placebo-Controlled Trial.
- 2025-05-18
- RCT · n = 35
- Nutrients 17(10)
- Lucrezia Laterza
- Cesare Cremon
- Gaetano Coppola
- Carlo Romano Settanni
- Rossella Maresca
- Martina Strazzeri
- Eleonora Durini
- Valentina Petito
- Franco Scaldaferri
- Giorgio Gargari
- Diego Mora
- Elnaz Vojoudi Yazdi
- Chiara Marangelo
- Gianluca Ianiro
- Lorenza Putignani
- Maria Raffaella Barbaro
- Giovanni Marasco
- Giovanni Barbara
- Antonio Gasbarrini
- PubMed: 40431448
- DOI: 10.3390/nu17101708
- High evidence
- Rigorous Journal
Lactate (p < 0.01) and acetate (p < 0.05) levels increased post-treatment.
- Beneficial
- Small effect
- Significant