Bifidobacterium lactis Bb-02 and Reduced Antibiotic-Associated Gut Microbiome Disruption

• Probiotic intervention not beneficial to prevent antibiotic-associated diarrhea in absence of antibiotic-induced microbiome disruption.

  • 2026-02-16
  • RCT
  • Scientific reports 16(1)
  • • Daniel Merenstein
    • Silvia Grant-Beurmann
    • Mary Ellen Sanders
    • Tina Tan
    • Brendan Burke
    • Aneesha Kumar
    • Keisha Herbin-Smith
    • Jessy Sparenborg
    • Frank D'Amico
    • Bob Roberts
    • Claire Fraser

  • PubMed: 41699149
  • DOI: 10.1038/s41598-026-39826-4

  2 Insights on

  • Reduced Antibiotic-Associated Gut Microbiome Disruption

  • High evidence
  • Rigorous Journal

  "The antibiotics used in our study did not disrupt the microbiome to the extent expected, which likely accounted for the low observed incidence of AAD."

  Effect

  Neutral

  Effect size

  Small