Bifidobacterium lactis Bb-02 and Reduced Cariogenic Bacteria

• The role of probiotics in preventing dental caries: a systematic review of clinical evidence.

  • 2025-12-02
  • Systematic Review
  • Frontiers in oral health 6
  • • Alessio Danilo Inchingolo
    • Angelo Michele Inchingolo
    • Irene Palumbo
    • Mariafrancesca Guglielmo
    • Lilla Riccaldo
    • Roberta Morolla
    • Francesco Inchingolo
    • Andrea Palermo
    • Gianna Dipalma

  • PubMed: 41409473
  • DOI: 10.3389/froh.2025.1720036

  5 Insights on

  • Reduced Cariogenic Bacteria

  • High evidence

  Most clinical trials reported a significant reduction in Streptococcus mutans levels following administration of probiotic strains, particularly Lactobacillus paracasei, Lactobacillus rhamnosus, and Bifidobacterium lactis.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

• The role of probiotics in modulating cariogenic bacteria and oral health outcomes: A systematic review and risk of bias assessment.

  • 2025-12
  • Review · n = 34
  • The Saudi dental journal 37(10-12)
  • • Rahayu Zulkapli
    • Faezah Sabirin
    • Anis Najihah Salleh
    • Nurul Zurain Fatiha Zulaidi
    • Iman Nabilah Abd Rahim
    • Muhammad Nazirul Mubin Aziz

  • PubMed: 41331162
  • DOI: 10.1007/s44445-025-00103-1

  5 Insights on

  • Reduced Cariogenic Bacteria

  • Moderate evidence

  Twenty-seven research studies demonstrated a significant reduction in the main cariogenic pathogen, Streptococcus mutans (p < 0.05 - p < 0.001)

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes