Bifidobacterium lactis BB-12 and Improved Intestinal Epithelial Permeability

• Probiotic Bifidobacterium strains and galactooligosaccharides improve intestinal barrier function in obese adults but show no synergism when used together as synbiotics

  • 2018-06-28
  • RCT
  • Microbiome 6(1)
  • • Janina A. Krumbeck
    • H. Rasmussen
    • R. Hutkins
    • Jennifer L Clarke
    • Krista M Shawron
    • A. Keshavarzian
    • J. Walter

  • PubMed: 29954454
  • DOI: 10.1186/s40168-018-0494-4

  3 Insights on

  • Improved Intestinal Epithelial Permeability

  • High evidence
  • Highly Cited

  Post-aspirin sucralose:lactulose ratios were reduced in groups IVS-1 (P = 0.050), ... indicating improvements in colonic permeability

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes