Comparison of qRT-PCR and ddPCR for multi-strain probiotic detection after a randomized human clinical trial.
- 2025-04-28
- Clinical Trial
- Frontiers in microbiology 16
- Nicolas Yeung
- Arthur C Ouwehand
- PubMed: 40356649
- DOI: 10.3389/fmicb.2025.1579797
- Moderate evidence
The ability to detect probiotic consumption during a human clinical trial is crucial to verify and validate placebo and verum groups in post hoc analysis... Moreover, we discovered that most of the sensitivity and specificity had come from a single assay alone (Bifidobacterium animalis subsp. lactis Bl-04).
- Effect
- Neutral
- Effect size
- Small