Bifidobacterium lactis BI-04 and No Conclusive Long-Term Clinical Benefit

• Microbiological Analyses of Subgingival Flora in Response to Probiotic Adjuncts to Non-surgical Periodontal Therapy: A Scoping Review.

  • 2026-01-02
  • Review
  • Cureus 18(1)
  • • Bernis Aydin
    • Seray Z Ozturk
    • Emine Cifcibasi

  • PubMed: 41635337
  • DOI: 10.7759/cureus.100604

  4 Insights on

  • No Conclusive Long-Term Clinical Benefit

  • Low evidence

  persistent microbial stability, durable colonization, and sustained clinical advantages have not been conclusively demonstrated.

  Effect

  Neutral

  Effect size

  Small