Bifidobacterium lactis BL818 and Healthy Age-Appropriate Growth

• Partially hydrolyzed, whey-based infant formula with six human milk oligosaccharides, B. infantis LMG11588, and B. lactis CNCM I-3446 is safe, well tolerated, and improves gut health: a staged analysis of a randomized trial.

  • 2025-07-23
  • RCT · n = 313
  • Frontiers in nutrition 12
  • • Jean-Charles Picaud
    • Olivier Claris
    • Mercedes Gil-Campos
    • Ignacio Salamanca De La Cueva
    • Luc Cornette
    • Philippe Alliet
    • André Léké
    • Mireille Castanet
    • Hugues Piloquet
    • Virginie de Halleux
    • Delphine Mitanchez
    • Yvan Vandenplas
    • Pierre Maton
    • Frank Jochum
    • Dirk Olbertz
    • Sergio Negre Policarpo
    • Luca Lavalle
    • Cecilia Fumero
    • Paula Rodriguez-Garcia
    • Janne Marie Moll
    • Irma Silva-Zolezzi
    • Boutaina Zemrani
    • Nicholas P Hays
    • Norbert Sprenger
    • Javier Miranda-Mallea

  • PubMed: 40771223
  • DOI: 10.3389/fnut.2025.1628847

  2 Insights on

  • Healthy Age-Appropriate Growth

  • High evidence

  The synbiotic-supplemented infant formula supported healthy, age-appropriate growth

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes