Bifidobacterium lactis HN019 and Improved Bowel Movements

• Eight-Week Supplementation With Bifidobacterium lactis HN019 and Functional Constipation: A Randomized Clinical Trial.

  • 2024-10-02
  • RCT · n = 283
  • JAMA network open 7(10)
  • • Jing Cheng
    • Carl Gao
    • Reeta Ala-Jaakkola
    • Sofia D Forssten
    • Markku Saarinen
    • Ashley Hibberd
    • Arthur C Ouwehand
    • Alvin Ibarra
    • Dingqiang Li
    • Anders Nordlund
    • Yingxin Wang
    • Xizhong Shen
    • Haixia Peng
    • Xinjian Wan
    • Xiangjun Meng

  • PubMed: 39356506
  • DOI: 10.1001/jamanetworkopen.2024.36888

  4 Insights on

  • Improved Bowel Movements

  • High evidence
  • Large Human Trial

  There was no difference in the change of weekly CSBMs from baseline to the end of study between the HN019 ... and placebo ... groups.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

  Dose

  7.0×10^9 CFU/day at start and 4.69×10^9 CFU/day at end of study