Bifidobacterium lactis HN019 and Improved Periodontal Health

• Probiotics in Periodontal Diseases: Mechanisms, Evidence Mapping, Limitations, and Future Directions.

  • 2025-11-03
  • Review
  • Cureus 17(11)
  • • Hamza Alasbily
    • Huda H Mohamed
    • Adnan Asheibi
    • Manal S Bazina
    • Ali Alkaseh
    • Hana M Ghaith
    • Fardous Ali Fahmi

  • PubMed: 41356942
  • DOI: 10.7759/cureus.96042

  1 Insight on

  • Improved Periodontal Health

  • Low evidence

  Probiotics have emerged as a possible alternative or supplement in periodontal therapy. Their possible benefits include microbial balance restoration in the oral cavity, as well as anti-inflammatory, immunomodulatory, and bone-preserving actions.

  Effect

  Beneficial

  Effect size

  Moderate

• Effects of live and heat-killed Bifidobacterium lactis in rats with induced periodontitis.

  • 2026-03-11
  • n = 32
  • Journal of applied oral science : revista FOB 34
  • • Tainá da Silva Tricoly
    • Thais Aguiar Santos
    • Camila Lopes Ferreira
    • Itza Amarilis Ribeiro Pinto
    • Victoria Clara da Silva Lima
    • Camilla Magnoni Moretto Nunes
    • Ana Lia Anbinder
    • Maria Aparecida Neves Jardini

  • PubMed: 41810630
  • DOI: 10.1590/1678-7765-2025-0634

  1 Insight on

  • Improved Periodontal Health

  • Low evidence
  • Animal Study

  Probiotic and postbiotic treatments did not improve outcomes... Bone loss was lowest in the control group, with no differences between EP, PRO, and POS.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No