Bifidobacterium lactis HN019 and Increased Short-Chain Fatty Acid Production

• Neuroprotective effects of Bifidobacterium animalis HN019 and Lactobacillus acidophilus NCFM in MPTP-induced Parkinson's disease mice.

  • 2026-03
  • Brain, behavior, and immunity 133
  • • Chengjun Mo
    • Yiwei Qian
    • Yi Zhang
    • Xiaoqin He
    • Yiqiu Lai
    • Shaoqing Xu
    • Penghui Ai
    • Xiaodong Yang
    • Qin Xiao

  • PubMed: 41513011
  • DOI: 10.1016/j.bbi.2026.106257

  6 Insights on

  • Increased Short-Chain Fatty Acid Production

  • Low evidence
  • Animal Study

  The relative abundances of propionate- and butyrate-producing bacteria, their biosynthetic pathways, and the critical enzymes were all elevated in the gut microbiota of probiotic-treated mice.

  Effect

  Beneficial

  Effect size

  Moderate

• Probiotics Attenuate Food Allergy via Short-Chain Fatty Acids-Mediated Immune Modulation and Gut Barrier Restoration.

  • 2025-11-18
  • Foods (Basel, Switzerland) 14(22)
  • • Xue Feng
    • Liuying Li
    • Li Yan
    • Zhencong Yan
    • Zhoujin Xu
    • Yuting Fan
    • Philippe Madjirebaye
    • Xuli Wu

  • PubMed: 41300111
  • DOI: 10.3390/foods14223953

  5 Insights on

  • Increased Short-Chain Fatty Acid Production

  • Low evidence

  Protection was underpinned by microbiota remodeling, marked by increased α-diversity and enrichment of SCFA-producing taxa (Lachnospiraceae and Muribaculaceae), which correlated with elevated acetate, butyrate, and propionate levels.

  Effect

  Beneficial

  Effect size

  Moderate