Bifidobacterium lactis HN019 and Reduced Asthma Prevalence

• Effects of Lactobacillus rhamnosus HN001 in early life on the cumulative prevalence of allergic disease to 11 years

  • 2018-11-14
  • RCT
  • Pediatric Allergy and Immunology 29(8)
  • • K. Wickens
    • C. Barthow
    • E. Mitchell
    • Janice Kang
    • N. van Zyl
    • G. Purdie
    • T. Stanley
    • P. Fitzharris
    • R. Murphy
    • J. Crane

  • PubMed: 30430649
  • DOI: 10.1111/pai.12982

  10 Insights on

  • Reduced Asthma Prevalence

  • High evidence
  • Rigorous Journal

  The abstract reports asthma as an outcome assessed but does not report a significant effect for HN001 on asthma at 11 years; no significant finding is stated for asthma, implying non-significance

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

  Dose

  6 × 10^9 cfu daily from 35-week gestation to 6 months' post-partum in mothers while breastfeeding and from birth to age 2 years in infants