Bifidobacterium lactis MAK16B42L and Improved Intestinal Function

• Effect of the probiotic strain Bifidobacterium animalis subsp. lactis, BB-12®, on defecation frequency in healthy subjects with low defecation frequency and abdominal discomfort: a randomised, double-blind, placebo-controlled, parallel-group trial

  • 2015-09-18
  • RCT · n = 1,248
  • British Journal of Nutrition 114(10)
  • • D. Eskesen
    • L. Jespersen
    • B. Michelsen
    • P. Whorwell
    • S. Müller-lissner
    • Cathrine M Morberg

  • PubMed: 26382580
  • DOI: 10.1017/S0007114515003347

  9 Insights on

  • Improved Intestinal Function

  • High evidence
  • Large Human Trial
  • Clinical

  Tightening the criteria for being a responder to an increase of ≥1 d/week for ≥50 % of the time resulted in an OR of 1·55 (95% CI 1·22, 1·96), P=0·0003, for treatment overall.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes