Bifidobacterium lactis MAK16B42L and Increased Anti-Inflammatory Cytokine Levels

• Effects of the probiotic Bifidobacterium animalis subsp. lactis on the non-surgical treatment of periodontitis. A histomorphometric, microtomographic and immunohistochemical study in rats

  • 2017-06-29
  • RCT · n = 32
  • PLOS ONE 12(6)
  • • M. S. Ricoldi
    • F. Furlaneto
    • L. Oliveira
    • G. C. Teixeira
    • Jéssica P Pischiotini
    • A. L. Moreira
    • E. Ervolino
    • M. N. de Oliveira
    • C. Bogsan
    • S. Salvador
    • M. Messora

  • PubMed: 28662142
  • DOI: 10.1371/journal.pone.0179946

  7 Insights on

  • Increased Anti-Inflammatory Cytokine Levels

  • Low evidence
  • Rigorous Journal
  • Animal Study

  Group EP-SRP-PROB showed significantly fewer osteoclasts, increased expression of anti-inflammatory cytokines and reduced expression of proinflammatory cytokines compared with Group EP-SRP (p<0.05).

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes