Bifidobacterium lactis MAK16B42L and Reduced Gastrointestinal Inflammation

• Effects of Bifidobacterium animalis ssp. lactis 420 on gastrointestinal inflammation induced by a nonsteroidal anti‐inflammatory drug: A randomized, placebo‐controlled, double‐blind clinical trial

  • 2021-05-30
  • RCT
  • British Journal of Clinical Pharmacology 87(12)
  • • S. Mäkelä
    • S. Forssten
    • M. Kailajärvi
    • V. Langén
    • M. Scheinin
    • K. Tiihonen
    • A. Ouwehand

  • PubMed: 33908058
  • DOI: 10.1111/bcp.14880

  1 Insight on

  • Reduced Gastrointestinal Inflammation

  • Low evidence
  • Animal Study

  Short-term administration of the probiotic B420 did not protect the healthy adult study participants from diclofenac-induced gastrointestinal inflammation as determined by analysis of faecal calprotectin levels.

  Effect

  Neutral

  Effect size

  Small

  Significant

  No