Bifidobacterium lactis UABla-12 and Altered Metabolite Profile

• Impact of Probiotic Formula (Lacto-5X) on Constipation: Improvements in Gastrointestinal Symptoms, Gut Microbiome, and Metabolites.

  • 2025-04-09
  • RCT
  • Journal of microbiology and biotechnology 35
  • • Yoo-Jeong Jin
    • Young Jae Park
    • Jieun Choi
    • Myung-Soo Kim
    • Uigi Min
    • Jonghyun Lim
    • Jooyeon Kang
    • Do Yup Lee
    • Byung-Yong Kim

  • PubMed: 40223270
  • DOI: 10.4014/jmb.2412.12056

  2 Insights on

  • Altered Metabolite Profile

  • High evidence

  Metabolome analysis showed that L-proline level in the Probiotic group decreased, while threonic acid level increased at the 4-week endpoint compared to the Placebo group.

  Effect

  Beneficial

  Effect size

  Small